• Brand: Premier Research Labs
  • Serving Size: 1 Capsule
  • Servings Per Container: 90
Price: $27.91


    Joint, Ligament and Connective Tissue Support

    Glucosamine Sulfate is a natural molecule made by the body, composed of glucose and an amine (nitrogen and two molecules of hydrogen). Research shows that glucosamine plays a key role in helping to keep all the joints in the body lubricated and supple. It stimulates the manufacture of glycosaminologycans, key structural components in cartilage which line the joints. Glucosamine also promotes the incorporation of sulfur into cartilage. Because of this effect, research shows that glucosamine sulfate is the most effective form.

    Who Gets Joint Disease?

    Over 40 million Americans have degenerative joint disease, including 80% of people over age 50. Under age 45, degenerative joint disease is more common in men; after age 45; it is ten times more common in women. The weight-bearing joints, such as the hips and knees, as well as the joints of the hands are often the most affected.

    As people age, many lose their ability to manufacture sufficient amounts of glucosamine. This may be the major factor leading to the degeneration of joints, which causes painful joint movement and destruction of the joint's cartilage. When injury occurs, the demand for collagen and other joint repair substances increases. Glucosamine is the rate-limiting factor in making many of these connective tissue and joint repair substances.

    Get the Best Form of Glucosamine

    Glucosamine comes in several forms: glucosamine sulfate, glucosamine hydrochloride and N-acetyl-glucosamine (NAG). Research shows that glucosamine sulfate far surpasses other glucosamines with joint-improving benefits. In fact, research has shown glucosamine hydrochloride to have little joint-improving benefits in comparison to glucosamine sulfate. Some marketing companies have claimed the NAG is better absorbed and more stable, but scientific research does not support this. It is best to stick with the glucosamine that delivers proven results every time.

    NSAIDs - Increased Joint Destruction

    A serious side effect of NSAIDs (nonsteroidal anti-inflammatory drugs) is that they can increase the inhibition of cartilage repair and accelerate cartilage destruction. Although aspirin and NSAIDs may initially help control joint pain, later they may worsen the individual's joint condition. Clinical studies have shown that the use of NSAIDs has accelerated joint destruction in osteoarthritis. Many doctors now avoid the use of NSAIDs. In contrast, glucosamine sulfate is a nutritional supplement which is safe, effective and has no side effects.

    Numerous double-blind studies have shown glucosamine sulfate produces better results than NSAIDs and placebos in controlling pain and inflammation of degenerative joint disease (such as osteoarthritis). One study suggested that to achieve the greatest effectiveness, higher amounts of glucosamine may be required for certain individuals: those who are obese, those who have peptic ulcers and those on diuretics. The study showed that even after the glucosamine was stopped, the people found their joint improvement continued for 6 to 12 weeks. This result indicates that glucosamine may be the most effective when taken continuously over long periods of time or in repeated short courses. Since glucosamine is safe and effective, long-term, continuous use in not a problem.

    Glucosamine Sulfate - A Natural Alternative to Asprin

    According to a well-known medical researcher, Dr. Michael Murray, "Glucosamine is a safe and effective natural alternative to aspirin and other nonsteroidal anti-inflammatory drugs." Clinical research shows that drugs currently being used to treat degenerative joint disease such as osteoarthritis may produce short-term relief, but in the long run, they actually accelerate the progression of joint destruction. Straight to the JointsGlucosamine is highly absorbed by the body. Detailed pharmaco-kinetic studies in animals and humans show up to 98% of orally administered glucosamine sulfate is absorbed. These studies show that after absorption, glucosamine sulfate is preferentially taken up by the cartilage and other joint structures where it stimulates the body's manufacture of chondroitin sulfate and other mucopolysaccharides. One of the key effects of glucosamine sulfate is its ability to stimulate the incorporation of sulfur into cartilage.

    No Sulfur Allergy

    Some people ask, "If I'm allergic to sulfur, can I take glucosamine sulfate?" When people say they are allergic to sulfur, they really mean they are allergic to so-called sulfa drugs or sulfite-containing food additives. It is impossible to be allergic to the mineral, sulfur since it is an essential mineral required for life. Glucosamine sulfate is extremely well tolerated; no allergic reactions have been reported.

    Recommended Use: For maintenance, Take 1 capsule 3 times daily with meals. For special programs for joint healing and repair, up to 10 capsules may be taken daily.


    Glucosamine Sulfate............................ 750mg

    Other Ingredients: 100% solvent-free, excipient-free vegetable capsules.

    Does Not Contain: Magnesium stearate (a toxic excipient), corn, milk, soy, salt, sugar, wheat, artificial colors, flavors, preservatives, binders, glues or other toxic tagalongs as found in tablets and gelatin capsules. Store in a cool, dry place.

    Violite™ Protected: Patent-pending dark violet-colored, #2 HDPE nontoxic plastic bottle engineered to block light between 450-720 nm, the range at which damage to nutrients occurs. Nitrogen flushed to protect freshness and prevent oxidation.